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Gastrointestinal perforation is a complete penetration of any part of the wall of the gastrointestinal tract, which lines the stomach, small intestine or large bowel, resulting in intestinal contents entering the abdominal cavity. Perforation of the intestines results in the potential for bacterial contamination of the abdominal cavity (a condition known as peritonitis). Perforation of the stomach can lead to a chemical peritonitis due to leaked gastric acid. Perforation anywhere along the gastrointestinal tract is a surgical emergency. ==Signs and symptoms== Sudden pain in the epigastrium to the right of the midline indicates perforation of a duodenal ulcer. In a gastric ulcer performation creates a history of burning pain in epigastrium, with flatulence and dyspepsia. A history of drug intake with insufficient food intake may be present. In intestinal perforation pain starts from the site of perforation and spreads across the abdomen. Gastrointestinal perforation results in severe abdominal pain intensified by movement, nausea, vomiting and hematemesis. Later symptoms include fever and or chills. In any case the abdomen becomes rigid with tenderness and rebound tenderness. After some time the abdomen becomes silent and heart sounds can be heard all over. Patient stops passing flatus and motion, abdomen is distended. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「gastrointestinal perforation」の詳細全文を読む スポンサード リンク
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